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CAS: | 477600-75-2 | Cat No: | JKN01040 | Purity: | 98% |
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Product Description
CAS | 477600-75-2 | Cat No | JKN01040 | |
Name | Tofacitinib | |||
Synonyms | Tofacitinib | |||
Smiles | C[C@@H]1CCN(C[C@@H]1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N | |||
Chemical Name | 3-[(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile | |||
Formula | C16H20N6O | MWt | 312.37 | |
Purity | 98% | Storage | Store at 4--8℃ | |
Description | Tofacitinib is a pyrrolopyrimidine that is pyrrolo[2,3-d]pyrimidine substituted at position 4 by an N-methyl,N-(1-cyanoacetyl-4-methylpiperidin-3-yl)amino moiety. Used as its citrate salt to treat moderately to severely active rheumatoid arthritis. It has a role as an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor and an antirheumatic drug. It is a pyrrolopyrimidine, a N-acylpiperidine, a nitrile and a tertiary amino compound. |
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