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| CAS: | 475108-18-0 | Cat No: | JKN00975 | Purity: | 98% |
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Product Description
| CAS | 475108-18-0 | Cat No | JKN00975 | |
| Name | Tivozanib | |||
| Synonyms | Tivozanib | |||
| Smiles | CC1=CC(=NO1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)Cl | |||
| Chemical Name | 1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(5-methyl-1,2-oxazol-3-yl)urea | |||
| Formula | C22H19ClN4O5 | MWt | 454.9 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Tivozanib is a member of the class of quinolines that is 6,7-dimethoxyquinoline substituted by a 3-chloro-4-{[(5-methyl-1,2-oxazol-3-yl)carbamoyl]amino}phenoxy group at position 4. It is a potent and selective inhibitor of VEGF receptor tyrosine kinases and was previously in clinical development for the treatment of metastatic renal cell carcinoma. It has a role as a vascular endothelial growth factor receptor antagonist, an antineoplastic agent and an apoptosis inducer. It is an aromatic ether, a member of isoxazoles, a member of phenylureas, a member of monochlorobenzenes and a member of quinolines. | |||
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