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| CAS: | 183204-74-2 | Cat No: | JKN00973 | Purity: | 98% |
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Product Description
| CAS | 183204-74-2 | Cat No | JKN00973 | |
| Name | Tipiracil | |||
| Synonyms | Tipiracil | |||
| Smiles | C1CC(=N)N(C1)CC2=C(C(=O)NC(=O)N2)Cl | |||
| Chemical Name | 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1H-pyrimidine-2,4-dione | |||
| Formula | C9H11ClN4O2 | MWt | 242.66 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Tipiracil is a member of the class of pyrimidones that is uracil substituted by chloro and (2-iminopyrrolidin-1-yl)methyl groups at positions 5 and 6 respectively. Used (as the hydrochloride salt) in combination with trifluridine, a nucleoside metabolic inhibitor, for treatment of advanced/relapsed unresectable colorectal cancer. It has a role as an antineoplastic agent and an EC 2.4.2.4 (thymidine phosphorylase) inhibitor. It is a pyrimidone, an organochlorine compound, a carboxamidine and a member of pyrrolidines. It is functionally related to a uracil. It is a conjugate base of a tipiracil(1+). | |||
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