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| CAS: | 941678-49-5 | Cat No: | JKN01034 | Purity: | 98% |
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Product Description
| CAS | 941678-49-5 | Cat No | JKN01034 | |
| Name | Ruxolitinib | |||
| Synonyms | Ruxolitinib | |||
| Smiles | C1CCC(C1)[C@@H](CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3 | |||
| Chemical Name | (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile | |||
| Formula | C17H18N6 | MWt | 306.4 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Ruxolitinib is a pyrazole substituted at position 1 by a 2-cyano-1-cyclopentylethyl group and at position 3 by a pyrrolo[2,3-d]pyrimidin-4-yl group. Used as the phosphate salt for the treatment of patients with intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis and post-essential thrombocythemia myelofibrosis. It has a role as an antineoplastic agent and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a nitrile, a pyrrolopyrimidine and a member of pyrazoles. | |||
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