Pharmaceutical intermediates

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Regorafenib Monohydrate

CAS: 1019206-88-2 Cat No: JKN00894 Purity: 98%

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Product Description

CAS 1019206-88-2 Cat No JKN00894
Name Regorafenib Monohydrate
Synonyms regorafenib monohydrate
Smiles CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F.O
Chemical Name 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide;hydrate
Formula C21H17ClF4N4O4 MWt 500.8
Purity 98% Storage Store at 4--8℃
Description Regorafenib hydrate is a hydrate that is the monohydrate form of anhydrous regorafenib. Used for for the treatment of metastatic colorectal cancer in patients who have previously received chemotherapy, anti-EGFR or anti-VEGF therapy. It has a role as an antineoplastic agent, a tyrosine kinase inhibitor and a hepatotoxic agent. It contains a regorafenib.

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