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| CAS: | 1114544-31-8 | Cat No: | JKN00870 | Purity: | 98% |
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Product Description
| CAS | 1114544-31-8 | Cat No | JKN00870 | |
| Name | Ponatinib Hydrochloride | |||
| Synonyms | Ponatinib hydrochloride | |||
| Smiles | CC1=C(C=C(C=C1)C(=O)NC2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)C#CC4=CN=C5N4N=CC=C5.Cl | |||
| Chemical Name | 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide;hydrochloride | |||
| Formula | C29H28ClF3N6O | MWt | 569.0 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Ponatinib hydrochloride is the hydrochloride salt of ponatinib. It is a potent pan inhibitor of tyrosine kinases, active in all single resistance ABL kinase mutations including the T315l mutation. It is approved for the treatment of chronic myeloid leukemia. It has a role as an antineoplastic agent and a tyrosine kinase inhibitor. It contains a ponatinib(1+). | |||
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