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| CAS: | 198470-85-8 | Cat No: | JKN00860 | Purity: | 98% |
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Product Description
| CAS | 198470-85-8 | Cat No | JKN00860 | |
| Name | Parecoxib Sodium | |||
| Synonyms | Parecoxib sodium | |||
| Smiles | CCC(=O)[N-]S(=O)(=O)C1=CC=C(C=C1)C2=C(ON=C2C3=CC=CC=C3)C.[Na+] | |||
| Chemical Name | sodium;[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)phenyl]sulfonyl-propanoylazanide | |||
| Formula | C19H17N2NaO4S | MWt | 392.4 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Parecoxib Sodium is a water-soluble, injectable sodium salt form of parecoxib, an amide prodrug of the cyclooxygenase II (COX-2) selective, non-steroidal anti-inflammatory drug (NSAID) valdecoxib, with anti-inflammatory, analgesic, and antipyretic activities. Upon intravenous or intramuscular administration, parecoxib is hydrolyzed by hepatic carboxyesterases to its active form, valdecoxib. Valdecoxib selectively binds to and inhibits COX-2. This prevents the conversion of arachidonic acid into prostaglandins, which are involved in the regulation of pain, inflammation, and fever. This NSAID does not inhibit COX-1 at therapeutic concentrations and, therefore, does not interfere with blood coagulation. | |||
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