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| CAS: | 404950-80-7 | Cat No: | JKN01036 | Purity: | 98% |
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Product Description
| CAS | 404950-80-7 | Cat No | JKN01036 | |
| Name | Panobinostat | |||
| Synonyms | Panobinostat | |||
| Smiles | CC1=C(C2=CC=CC=C2N1)CCNCC3=CC=C(C=C3)/C=C/C(=O)NO | |||
| Chemical Name | (E)-N-hydroxy-3-[4-[[2-(2-methyl-1H-indol-3-yl)ethylamino]methyl]phenyl]prop-2-enamide | |||
| Formula | C21H23N3O2 | MWt | 349.4 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Panobinostat is a hydroxamic acid obtained by formal condensation of the carboxy group of (2E)-3-[4-({[2-(2-methylindol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enoic acid with the amino group of hydroxylamine. A histone deacetylase inhibitor used (as its lactate salt) in combination with bortezomib and dexamethasone for the treatment of multiple myeloma. It has a role as an EC 3.5.1.98 (histone deacetylase) inhibitor, an antineoplastic agent and an angiogenesis modulating agent. It is a hydroxamic acid, a member of cinnamamides, a secondary amino compound and a methylindole. It is a conjugate base of a panobinostat(1+). | |||
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