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| CAS: | 936446-61-6 | Cat No: | JKN00844 | Purity: | 98% |
Note: All products of the company are for scientific research only, and do not provide products and services for any individual
Product Description
| CAS | 936446-61-6 | Cat No | JKN00844 | |
| Name | Nrc-2694 | |||
| Synonyms | NRC-2694 | |||
| Smiles | COC1=C(C=C2C(=C1)N=CN=C2NC3=CC=CC(=C3)C#C)OCCCN4CCOCC4 | |||
| Chemical Name | N-(3-ethynylphenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine | |||
| Formula | C24H26N4O3 | MWt | 418.5 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | EGFR Inhibitor NRC-2694 is an orally bioavailable, small-molecule inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity. Upon oral administration, EGFR inhibitor NRC-2694 binds to and inhibits EGFR, which prevents EGFR-mediated signaling and leads to cell death in EGFR-expressing tumor cells. EGFR, a receptor tyrosine kinase mutated in many tumor cell types, plays a key role in tumor cell proliferation and tumor vascularization. | |||
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