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| CAS: | 1038915-73-9 | Cat No: | JKN00806 | Purity: | 98% |
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Product Description
| CAS | 1038915-73-9 | Cat No | JKN00806 | |
| Name | Niraparib tosylate | |||
| Synonyms | MK-4827 | |||
| Smiles | CC1=CC=C(C=C1)S(=O)(=O)O.C1C[C@H](CNC1)C2=CC=C(C=C2)N3C=C4C=CC=C(C4=N3)C(=O)N | |||
| Chemical Name | 4-methylbenzenesulfonic acid;2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide | |||
| Formula | C26H28N4O4S | MWt | 492.6 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Niraparib Tosylate (also known as MK-4827; MK4827; Zejula), the tosylate salt of niraparib, is an orally bioavailable and selective inhibitor of PARP1/2 (IC50 = 3.8 nM and 2.1nM) that gained FDA approval in March 2017 for the treatment of recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer. | |||
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