Pharmaceutical intermediates

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Fosinopril Sodium

CAS: 88889-14-9 Cat No: JKN00724 Purity: 98%

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Product Description

CAS 88889-14-9 Cat No JKN00724
Name Fosinopril Sodium
Synonyms FOSINOPRIL SODIUM
Smiles CCC(=O)OC(C(C)C)OP(=O)(CCCCC1=CC=CC=C1)CC(=O)N2C[C@@H](C[C@H]2C(=O)[O-])C3CCCCC3.[Na+]
Chemical Name sodium;(2S,4S)-4-cyclohexyl-1-[2-[(2-methyl-1-propanoyloxypropoxy)-(4-phenylbutyl)phosphoryl]acetyl]pyrrolidine-2-carboxylate
Formula C30H45NNaO7P MWt 585.6
Purity 98% Storage Store at 4--8℃
Description Fosinopril sodium is the sodium salt of fosinopril. It is used for the treatment of hypertension and heart failure. A pro-drug, its phosphinate ester group is hydrolysed in vivo to give the corresponding phosphininc acid, fosinoprilat, which is the active metabolite. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor, a prodrug and an antihypertensive agent. It contains a fosinopril(1-).

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