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| CAS: | 209783-80-2 | Cat No: | JKN00689 | Purity: | 98% |
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Product Description
| CAS | 209783-80-2 | Cat No | JKN00689 | |
| Name | Entinostat | |||
| Synonyms | Entinostat | |||
| Smiles | C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3 | |||
| Chemical Name | pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate | |||
| Formula | C21H20N4O3 | MWt | 376.4 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Entinostat is a member of the class of benzamides resulting from the formal condensation of the carboxy group of the pyridin-3-ylmethyl carbamate derivative of p-(aminomethyl)benzoic acid with one of the amino groups of benzene-1,2-diamine. It is an inhibitor of histone deacetylase isoform 1 (HDAC1) and isoform 3 (HDAC3). It has a role as an EC 3.5.1.98 (histone deacetylase) inhibitor, an antineoplastic agent and an apoptosis inducer. It is a member of pyridines, a carbamate ester, a substituted aniline, a primary amino compound and a member of benzamides. It is functionally related to a 1,2-phenylenediamine. | |||
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