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| CAS: | 1599440-33-1 | Cat No: | JKN00674 | Purity: | 98% |
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Product Description
| CAS | 1599440-33-1 | Cat No | JKN00674 | |
| Name | Dxd | |||
| Synonyms | DX-8951 | |||
| Smiles | CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C5[C@H](CCC6=C5C(=CC(=C6C)F)N=C4C3=C2)NC(=O)CO)O | |||
| Chemical Name | N-[(10S,23S)-10-ethyl-18-fluoro-10-hydroxy-19-methyl-5,9-dioxo-8-oxa-4,15-diazahexacyclo[14.7.1.02,14.04,13.06,11.020,24]tetracosa-1,6(11),12,14,16,18,20(24)-heptaen-23-yl]-2-hydroxyacetamide | |||
| Formula | C26H24FN3O6 | MWt | 493.5 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Dxd,an exatecan analog, is a novel and potent DNA topoisomerase I inhibitor(IC50=0.31 μM) with anticancer activity, and is used as a conjugated drug of HER2-targeting ADC | |||
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