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| CAS: | 755038-02-9 | Cat No: | JKN00554 | Purity: | 98% |
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Product Description
| CAS | 755038-02-9 | Cat No | JKN00554 | |
| Name | Bi-2536 | |||
| Synonyms | BI 2536 | |||
| Smiles | CC[C@@H]1C(=O)N(C2=CN=C(N=C2N1C3CCCC3)NC4=C(C=C(C=C4)C(=O)NC5CCN(CC5)C)OC)C | |||
| Chemical Name | 4-[[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-7H-pteridin-2-yl]amino]-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide | |||
| Formula | C28H39N7O3 | MWt | 521.7 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | BI-2536 is a member of the class of tetrahydropterins that is 7,8-dihydropteridin-6(5H)-one substituted by {2-methoxy-4-[(1-methylpiperidin-4-yl)carbamoyl]phenyl}amino, methyl, ethyl, and cyclopentyl groups at positions 2, 5, 7R, and 8, respectively. It is a polo-like kinase 1 (PLK1) inhibitor with antineoplastic activity. It has a role as an EC 2.7.11.21 (polo kinase) inhibitor, an antineoplastic agent and an apoptosis inducer. It is a member of cyclopentanes, a tetrahydropterin, a monomethoxybenzene, a substituted aniline, a member of benzamides, a secondary carboxamide, a member of piperidines, a secondary amino compound and a tertiary amino compound. | |||
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