Pharmaceutical intermediates

Jingkangen Biomedical provides different types of Pharmaceutical intermediates ranging from milligrams to kilograms scale (1000kg) with high quality and competitive prices.

Bedaquiline

CAS: 843663-66-1 Cat No: JKN00367 Purity: 98%

Note: All products of the company are for scientific research only, and do not provide products and services for any individual

Product Description

CAS 843663-66-1 Cat No JKN00367
Name Bedaquiline
Synonyms Bedaquiline
Smiles CN(C)CC[C@@](C1=CC=CC2=CC=CC=C21)([C@H](C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O
Chemical Name (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-naphthalen-1-yl-1-phenylbutan-2-ol
Formula C32H31BrN2O2 MWt 555.5
Purity 98% Storage Store at 4--8℃
Description Bedaquiline is a quinoline-based antimycobacterial drug used (as its fumarate salt) for the treatment of pulmonary multi-drug resistant tuberculosis by inhibition of ATP synthase, an enzyme essential for the replication of the mycobacteria. It has a role as an antitubercular agent and an ATP synthase inhibitor. It is a member of quinolines, a member of naphthalenes, an organobromine compound, an aromatic ether, a tertiary alcohol and a tertiary amino compound. It is a conjugate base of a bedaquiline(2+).

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