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CAS: | 249921-19-5 | Cat No: | JKN00515 | Purity: | 98% |
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Product Description
CAS | 249921-19-5 | Cat No | JKN00515 | |
Name | Anamorelin | |||
Synonyms | Anamorelin | |||
Smiles | CC(C)(C(=O)N[C@H](CC1=CNC2=CC=CC=C21)C(=O)N3CCC[C@](C3)(CC4=CC=CC=C4)C(=O)N(C)N(C)C)N | |||
Chemical Name | 2-amino-N-[(2R)-1-[(3R)-3-benzyl-3-[dimethylamino(methyl)carbamoyl]piperidin-1-yl]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-methylpropanamide | |||
Formula | C31H42N6O3 | MWt | 546.7 | |
Purity | 98% | Storage | Store at 4--8℃ | |
Description | Anamorelin is a synthetic, orally bioavailable, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of ghrelin. Stimulation of GHSR may also reduce the production of the pro-inflammatory cytokines TNF-alpha and interleukin-6, which may play a direct role in cancer-related loss of appetite. |
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