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| CAS: | 850140-72-6 | Cat No: | JKN00371 | Purity: | 98% |
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Product Description
| CAS | 850140-72-6 | Cat No | JKN00371 | |
| Name | Afatinib | |||
| Synonyms | Afatinib | |||
| Smiles | CN(C)C/C=C/C(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)O[C@H]4CCOC4 | |||
| Chemical Name | (E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide | |||
| Formula | C24H25ClFN5O3 | MWt | 485.9 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Afatinib is a quinazoline compound having a 3-chloro-4-fluoroanilino group at the 4-position, a 4-dimethylamino-trans-but-2-enamido group at the 6-position, and an (S)-tetrahydrofuran-3-yloxy group at the 7-position. Used (as its dimaleate salt) for the first-line treatment of patients with metastatic non-small cell lung cancer. It has a role as a tyrosine kinase inhibitor and an antineoplastic agent. It is a member of quinazolines, a member of furans, an organofluorine compound, an enamide, an aromatic ether, a tertiary amino compound, a member of monochlorobenzenes and a secondary carboxamide. | |||
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