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CAS: | 2627-69-2 | Cat No: | JKN00488 | Purity: | 98% |
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Product Description
CAS | 2627-69-2 | Cat No | JKN00488 | |
Name | Acadesine | |||
Synonyms | NSC-105823 | |||
Smiles | C1=NC(=C(N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)N)C(=O)N | |||
Chemical Name | 5-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]imidazole-4-carboxamide | |||
Formula | C9H14N4O5 | MWt | 258.23 | |
Purity | 98% | Storage | Store at 4--8℃ | |
Description | Acadesine is a 1-ribosylimidazolecarboxamide in which the carboxamide group is situated at position 4 of the imidazole ring, which is further substituted at position 5 by an amino group. A purine nucleoside analogue and activator of AMP-activated protein kinase, it is is used for the treatment of acute lymphoblastic leukemia and is reported to have cardioprotective effects. It has a role as a platelet aggregation inhibitor and an antineoplastic agent. It is an aminoimidazole, a nucleoside analogue and a 1-ribosylimidazolecarboxamide. |
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