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CAS: | 210344-95-9 | Cat No: | JKN00082 | Purity: | 98% |
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Product Description
CAS | 210344-95-9 | Cat No | JKN00082 | |
Name | Z-DEVD-fmk | |||
Synonyms | ZDEVDfmk | |||
Smiles | O=C(OC)CC[C@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)CC(OC)=O)=O)C(N[C@@H](C(C)C)C(N[C@H](C(CF)=O)CC(OC)=O)=O)=O | |||
Chemical Name | methyl (5S,8S,11S,14S)-14-(2-fluoroacetyl)-11-isopropyl-5-(2-methoxy-2-oxoethyl)-8-(3-methoxy-3-oxopropyl)-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate | |||
Formula | C30H41FN4O12 | MWt | 668.670 | |
Purity | 98% | Storage | Store at 4--8℃ | |
Description | Z-DEVD-FMK is a tetrapeptide fluoromethyl ketone inhibitor that selectively targets caspase-3, an essential executioner in apoptosis. By irreversibly binding to the enzyme’s active site, it prevents proteolytic cleavage of key substrates, effectively blocking apoptotic signaling. This compound is widely used in research to study programmed cell death and evaluate anti-apoptotic therapeutic strategies. |
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