Pharmaceutical intermediates

Jingkangen Biomedical provides different types of Pharmaceutical intermediates ranging from milligrams to kilograms scale (1000kg) with high quality and competitive prices.

Z-DEVD-fmk

CAS: 210344-95-9 Cat No: JKN00082 Purity: 98%

Note: All products of the company are for scientific research only, and do not provide products and services for any individual

Product Description

CAS 210344-95-9 Cat No JKN00082
Name Z-DEVD-fmk
Synonyms ZDEVDfmk
Smiles O=C(OC)CC[C@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)CC(OC)=O)=O)C(N[C@@H](C(C)C)C(N[C@H](C(CF)=O)CC(OC)=O)=O)=O
Chemical Name methyl (5S,8S,11S,14S)-14-(2-fluoroacetyl)-11-isopropyl-5-(2-methoxy-2-oxoethyl)-8-(3-methoxy-3-oxopropyl)-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate
Formula C30H41FN4O12 MWt 668.670
Purity 98% Storage Store at 4--8℃
Description Z-DEVD-FMK is a tetrapeptide fluoromethyl ketone inhibitor that selectively targets caspase-3, an essential executioner in apoptosis. By irreversibly binding to the enzyme’s active site, it prevents proteolytic cleavage of key substrates, effectively blocking apoptotic signaling. This compound is widely used in research to study programmed cell death and evaluate anti-apoptotic therapeutic strategies.

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