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Home - Products-JKN Signaling Pathways-YF-135

YF-135

CAS:

2913177-53-2

Cat No:

JKN03177

Purity:

98%

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Note: All products of the company are for scientific research only, and do not provide products and services for any individual

Product Description

CAS	2913177-53-2	Cat No	JKN03177
Name	YF-135
Synonyms	YF135
Smiles	CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)(C)C)NC(=O)CCOCCCN4CCC[C@H]4COC5=NC6=C(CCN(C6)C7=CC=CC8=C7C(=CC=C8)Cl)C(=N5)N9CCN([C@H](C9)CC#N)C(=O)/C(=C/C1CC1)/C#N)O
Chemical Name	(2S,4R)-1-[(2S)-2-[3-[3-[(2S)-2-[[7-(8-chloronaphthalen-1-yl)-4-[(3S)-4-[(E)-2-cyano-3-cyclopropylprop-2-enoyl]-3-(cyanomethyl)piperazin-1-yl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]oxymethyl]pyrrolidin-1-yl]propoxy]propanoylamino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
Formula	C63H75ClN12O7S	MWt	1179.9
Purity	98%	Storage	Store at 4--8℃
Description	YF135 is a highly efficient reversible covalent KRASG12C PROTAC.

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