+86 137 2013 4139
+86 137 2013 4139
| CAS: | 2647442-33-7 | Cat No: | JKN08997 | Purity: | 98% |
Note: All products of the company are for scientific research only, and do not provide products and services for any individual
VV116 (Mindeudesivir) is an innovative oral antiviral nucleoside prodrug that inhibits viral replication by targeting RNA-dependent RNA polymerase (RdRp). JKN Biochem provides high-purity, traceable VV116 suitable for research institutions and pharmaceutical R&D procurement.
● High-purity research compound, ideal for drug development and experimental studies
● Oral bioavailability superior to Remdesivir, broad-spectrum antiviral potential
● Strict quality control with batch-to-batch consistency
● Flexible supply: from milligram to kilogram scale for research and development
VV116 is metabolized in vivo to the active nucleoside triphosphate, which binds to viral RNA-dependent RNA polymerase (RdRp) and inhibits RNA synthesis, suppressing SARS-CoV-2 and other coronavirus replication. As a deuterated derivative of Remdesivir, VV116 offers improved oral absorption and pharmacokinetics.
● Global supplier of research compounds with professional B2B services
● Flexible scales to meet lab procurement and large-scale R&D needs
● High purity and stability ensured through strict QC
● Fast response and worldwide shipping to avoid research interruptions
Product Description
| CAS | 2647442-33-7 | Cat No | JKN08997 | |
| Name | Mindeudesivir | |||
| Synonyms | VV116 | |||
| Smiles | [2H]C1=C2C(=NC=NN2C(=C1)[C@]3([C@@H]([C@@H]([C@H](O3)COC(=O)C(C)C)OC(=O)C(C)C)OC(=O)C(C)C)C#N)N | |||
| Chemical Name | (2R,3R,4R,5R)-2-(4-amino-5-deuteropyrrolo[2,1-f][1,2,4]triazin-7-yl)-2-cyano-5-((isobutyryloxy)methyl)tetrahydrofuran-3,4-diyl bis(2-methylpropanoate) | |||
| Formula | C24H30DN5O7 | MWt | 502.54 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | VV-116 (also known as VV116, JT-001) is a novel, potent and orally administered anti-SARS-CoV-2 nucleoside drug candidate (IC50 = 0.67±0.24 μM) acting asa viral RNA-dependent RNA polymerase (RdRp) inhibitor and isunder investigation for COVID-19 treatment in China. | |||
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