Pharmaceutical intermediates

Jingkangen Biomedical provides different types of Pharmaceutical intermediates ranging from milligrams to kilograms scale (1000kg) with high quality and competitive prices.

VV116 hydrobromide

CAS: 2779498-79-0 Cat No: JKN08998 Purity: 98%

Note: All products of the company are for scientific research only, and do not provide products and services for any individual

VV116 Hydrobromide Antiviral Nucleoside Prodrug — High-Purity Research Compound

VV116 Hydrobromide (Mindeudesivir HBr) is an oral antiviral nucleoside prodrug and a Remdesivir analogue with high bioavailability. It inhibits viral replication by targeting RNA-dependent RNA polymerase (RdRp) and demonstrates potent activity against SARS-CoV-2 and respiratory syncytial virus (RSV). JKN Biochem supplies high-purity VV116 HBr for research and pharmaceutical R&D procurement.


Key Features & Advantages

● Highly pure research compound (98% purity) for experimental and drug development applications

● Oral bioactivity superior to Remdesivir, broad-spectrum antiviral potential

● Strict quality control ensures batch-to-batch consistency

● Flexible supply from milligrams to kilograms to meet laboratory and industrial research needs


Mechanism of Action

VV116 HBr is metabolized in vivo to its active nucleoside triphosphate, which binds viral RNA-dependent RNA polymerase (RdRp) and blocks RNA synthesis. This inhibits replication of SARS-CoV-2 and RSV. As a deuterated Remdesivir analogue, it offers improved oral absorption and favorable pharmacokinetics.


Why Choose JKN Biochem for VV116 HBr?

● Professional global supplier of research compounds with B2B services

● Flexible supply scales for lab procurement and R&D needs

● High-purity and stable compound verified by strict QC

● Fast response and international shipping ensures uninterrupted research


Product Description

CAS 2779498-79-0 Cat No JKN08998
Name Mindeudesivir hydrobromide
Synonyms VV116 hydrobromide
Smiles Br.O1[C@H](COC(C(C)C)=O)[C@H]([C@H]([C@]1(C#N)C1=CC([2H])=C2C(N)=NC=NN12)OC(C(C)C)=O)OC(C(C)C)=O
Chemical Name [(2R,3R,4R,5R)-5-(4-amino-5-deuteriopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-bis(2-methylpropanoyloxy)oxolan-2-yl]methyl 2-methylpropanoate;hydrobromide
Formula C24H31DBrN5O7 MWt 583.45
Purity 98% Storage Store at 4--8℃
Description Mindeudesivir (JT001; VV116; GS-621763-d1) HBr, an analogue of Remdesivir, is a highly orally bioactive nucleoside antiviral compound against SARS-CoV-2 and respiratory syncytial virus (RSV) infection

Product Documents

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E-mail: orders@jknbiochem.com

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