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VC-Pab-mmae

CAS:

644981-35-1

Cat No:

JKN03675

Purity:

98%

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Product Description

CAS	644981-35-1	Cat No	JKN03675
Name	VC-Pab-mmae
Synonyms	Val-Cit-PAB-MMAE
Smiles	CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@H](C)[C@H](C2=CC=CC=C2)O)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)N(C)C(=O)OCC3=CC=C(C=C3)NC(=O)[C@H](CCCNC(=O)N)NC(=O)[C@H](C(C)C)N
Chemical Name	[4-[[(2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]phenyl]methyl N-[(2S)-1-[[(2S)-1-[[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-N-methylcarbamate
Formula	C58H94N10O12	MWt	1123.4
Purity	98%	Storage	Store at 4--8℃
Description	Val-Cit-PAB-MMAE is a drug-linker conjugate used for preparing ADC (antibody-drug-conjugate) with monomethyl auristatin E (MMAE), a highly potent anti-mitotic agent as a cytotoxicin/warhead, linked via the peptide Val-Cit-PAB.

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