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CAS: | 1620820-12-3 | Cat No: | JKN03157 | Purity: | 98% |
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Product Description
CAS | 1620820-12-3 | Cat No | JKN03157 | |
Name | TL4-12 | |||
Synonyms | TL4-12 | |||
Smiles | CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3CCN(CC3)C)OC4=NC=NC(=C4)NC | |||
Chemical Name | 4-methyl-3-[6-(methylamino)pyrimidin-4-yl]oxy-N-[3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]benzamide | |||
Formula | C25H27F3N6O2 | MWt | 500.5 | |
Purity | 98% | Storage | Store at 4--8℃ | |
Description | TL4-12 is a selective MAP4K2/GCK inhibitor that downregulates IKZF1 and BCL-6, inhibits MM cell growth/proliferation (IC50=37 nM) and causes apoptosis. |
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