Pharmaceutical intermediates

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TL4-12

CAS: 1620820-12-3 Cat No: JKN03157 Purity: 98%

Note: All products of the company are for scientific research only, and do not provide products and services for any individual

Product Description

CAS 1620820-12-3 Cat No JKN03157
Name TL4-12
Synonyms TL4-12
Smiles CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3CCN(CC3)C)OC4=NC=NC(=C4)NC
Chemical Name 4-methyl-3-[6-(methylamino)pyrimidin-4-yl]oxy-N-[3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]benzamide
Formula C25H27F3N6O2 MWt 500.5
Purity 98% Storage Store at 4--8℃
Description TL4-12 is a selective MAP4K2/GCK inhibitor that downregulates IKZF1 and BCL-6, inhibits MM cell growth/proliferation (IC50=37 nM) and causes apoptosis.

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