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CAS: | 60084-10-8 | Cat No: | JKN03153 | Purity: | 98% |
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Product Description
CAS | 60084-10-8 | Cat No | JKN03153 | |
Name | Tiazofurin | |||
Synonyms | Tiazofurin | |||
Smiles | C1=C(N=C(S1)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)C(=O)N | |||
Chemical Name | 2-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-thiazole-4-carboxamide | |||
Formula | C9H12N2O5S | MWt | 260.27 | |
Purity | 98% | Storage | Store at 4--8℃ | |
Description | Tiazofurine is a C-glycosyl compound that is 1,3-thiazole-4-carboxamide in which the hydrogen at position 2 has been replaced by a beta-D-ribofuranosyl group. It is metabolised to thiazole-4-carboxamide adenine dinucleotide (TAD), a selective inhibitor of inosine monophosphate dehydrogenase (IMP dehydrogenase). It has a role as an EC 1.1.1.205 (IMP dehydrogenase) inhibitor, a prodrug and an antineoplastic agent. It is a C-glycosyl compound, a member of 1,3-thiazoles and a monocarboxylic acid amide. It is functionally related to a beta-D-ribose. |
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