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| CAS: | 908112-43-6 | Cat No: | JKN03316 | Purity: | 98% |
Note: All products of the company are for scientific research only, and do not provide products and services for any individual
Product Description
| CAS | 908112-43-6 | Cat No | JKN03316 | |
| Name | SNX-2112 | |||
| Synonyms | SNX-2112 | |||
| Smiles | ||||
| Chemical Name | 4-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)-2-((1r,4r)-4-hydroxycyclohexylamino)benzamide | |||
| Formula | C23H27F3N4O3 | MWt | 464.48 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | SNX-2112, also known as PF 04928473, is an Hsp90 inhibitor which is currently undergoing multiple phase 1 clinical trials. In all cell lines, SNX-2112 led to degradation of MET, HER-2, EGFR, and AKT as well as abrogation of Ras/Raf/MEK/MAPK and PI3K/AKT signaling, followed by complete cell cycle arrest. | |||
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