Pharmaceutical intermediates

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Smurf1-IN-A01

CAS: 1007647-73-5 Cat No: JKN03651 Purity: 98%

Note: All products of the company are for scientific research only, and do not provide products and services for any individual

Product Description

CAS 1007647-73-5 Cat No JKN03651
Name Smurf1-IN-A01
Synonyms Smurf1-IN-A01
Smiles CC1=CC=NN1C2=CC=C(C=C2)C(=O)N3CCN(CC3)S(=O)(=O)C4=CC(=C(C=C4)Cl)C(F)(F)F
Chemical Name [4-[4-chloro-3-(trifluoromethyl)phenyl]sulfonylpiperazin-1-yl]-[4-(5-methylpyrazol-1-yl)phenyl]methanone
Formula C22H20ClF3N4O3S MWt 512.9
Purity 98% Storage Store at 4--8℃
Description Smurf1-IN-A01is a novel, potent, high affinity and selective inhibitor of E3 ubiquitin-protein ligase Smurf1 (Smad ubiquitination regulatory factor-1) with Kd value of 3.7 nM.

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