Pharmaceutical intermediates

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Selisistat

CAS: 49843-98-3 Cat No: JKN00089 Purity: 98%

Note: All products of the company are for scientific research only, and do not provide products and services for any individual

Product Description

CAS 49843-98-3 Cat No JKN00089
Name Selisistat
Synonyms EX-527
Smiles O=C(C1C(NC2=C3C=C(Cl)C=C2)=C3CCC1)N
Chemical Name 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide
Formula C13H13ClN2O MWt 248.710
Purity 98% Storage Store at 4--8℃
Description Selisistat, also known as EX-527, is a SirT1 inhibitor for treatment of Huntington's disease. Selisistat is widely used as a major inhibitor of Sirtuin enzymes, which are a family of highly conserved protein deacetylases and have been linked with caloric restriction and aging by modulating energy metabolism, genomic stability, and stress resistance.

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