Pharmaceutical intermediates

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Ruxolitinib Phosphate

CAS: 1092939-17-7 Cat No: JKN03200 Purity: 98%

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Product Description

CAS 1092939-17-7 Cat No JKN03200
Name Ruxolitinib Phosphate
Synonyms Ruxolitinib phosphate
Smiles C1CCC(C1)[C@@H](CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OP(=O)(O)O
Chemical Name (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile;phosphoric acid
Formula C17H21N6O4P MWt 404.4
Purity 98% Storage Store at 4--8℃
Description Ruxolitinib phosphate is a phosphate salt obtained by reaction ruxolitinib with one equivalent of phosphoric acid. Used for the treatment of patients with intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis and post-essential thrombocythemia myelofibrosis. It has a role as an antineoplastic agent and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It contains a ruxolitinib.

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