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| CAS: | 1174018-99-5 | Cat No: | JKN00213 | Purity: | 98% |
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Product Description
| CAS | 1174018-99-5 | Cat No | JKN00213 | |
| Name | Relebactam | |||
| Synonyms | MK7655 | |||
| Smiles | O=S(O)(ON1[C@]2([H])CC[C@@H](C(NC3CCNCC3)=O)[N@@](C2)C1=O)=O | |||
| Chemical Name | (1R,2S,5R)-7-oxo-2-(piperidin-4-ylcarbamoyl)-1,6-diazabicyclo[3.2.1]octan-6-yl hydrogen sulfate | |||
| Formula | C12H20N4O6S | MWt | 348.370 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Relebactam, also known as MK-7655, is a non-β-lactam β-lactamase inhibitor that primarily targets class A (including KPC) and class C (AmpC) β-lactamases, thereby restoring the activity of β-lactam antibiotics such as imipenem. In combination with imipenem-cilastatin (marketed as Recarbrio), relebactam has shown potent in vitro activity against multidrug-resistant Gram-negative pathogens, particularly carbapenem-resistant Klebsiella pneumoniae and Pseudomonas aeruginosa. Minimum inhibitory concentration (MIC) data indicate that imipenem-relebactam reduces MIC values significantly compared to imipenem alone; for instance, the MIC₉₀ against P. aeruginosa is often ≤4 µg/mL versus >16 µg/mL for imipenem alone. | |||
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