Pharmaceutical intermediates

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Relebactam monohydrate

CAS: 1174020-13-3 Cat No: JKN03607 Purity: 98%

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Product Description

CAS 1174020-13-3 Cat No JKN03607
Name Relebactam monohydrate
Synonyms Relebactam monohydrate
Smiles C1C[C@H](N2C[C@@H]1N(C2=O)OS(=O)(=O)O)C(=O)NC3CCNCC3
Chemical Name [(2S,5R)-7-oxo-2-(piperidin-4-ylcarbamoyl)-1,6-diazabicyclo[3.2.1]octan-6-yl] hydrogen sulfate
Formula C12H20N4O6S MWt 348.38
Purity 98% Storage Store at 4--8℃
Description Relebactam is a diazabicyclooctane beta-lactamase inhibitor, similar in structure to [avibactam]. It includes a piperidine ring which reduces export from bacterial cells by producing a positive charge. It is currently available in a combination product which includes [imipenem] and [cilastatin] to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated intra-abdominal infections in adults. It is considered to be a last-line treatment option and gained FDA approval as part of the combination product RecarbrioⓇ in July 2019.

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