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| CAS: | 755037-03-7 | Cat No: | JKN00277 | Purity: | 98% |
Note: All products of the company are for scientific research only, and do not provide products and services for any individual
Product Description
| CAS | 755037-03-7 | Cat No | JKN00277 | |
| Name | Regorafenib | |||
| Synonyms | BAY-734506 | |||
| Smiles | C12=NC(NC3=CC=C(N4CCOCC4)C=C3)=NC(NC5CCCCC5)=C1NC=N2 | |||
| Chemical Name | 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide | |||
| Formula | C21H15ClF4N4O3 | MWt | 482.815 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Regorafenib, also known as BAY 73-4506; binds to and inhibits vascular endothelial growth factor receptors (VEGFRs) 2 and 3, and Ret, Kit, PDGFR and Raf kinases, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation. Regorafenib is seen to increase the overall survival of patients with metastatic colorectal cancer. | |||
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