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| CAS: | 431898-65-6 | Cat No: | JKN03129 | Purity: | 98% |
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Product Description
| CAS | 431898-65-6 | Cat No | JKN03129 | |
| Name | PS-1145 | |||
| Synonyms | PS-1145 | |||
| Smiles | C1=CC(=CN=C1)C(=O)NC2=CC(=CC3=C2NC4=C3C=CN=C4)Cl | |||
| Chemical Name | N-(6-chloro-9H-pyrido[3,4-b]indol-8-yl)pyridine-3-carboxamide | |||
| Formula | C17H11ClN4O | MWt | 322.7 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | PS-1145 is a member of the class of beta-carbolines that is 9H-beta-carboline substituted by chloro and (pyridin-3-ylcarbonyl)amino groups at positions 6 and 8, respectively. It is a IkappaB kinase beta (IKKbeta) inhibitor (IC50 = 88 nM). It has a role as an EC 2.7.11.10 (IkappaB kinase) inhibitor, an antineoplastic agent and an apoptosis inducer. It is a member of beta-carbolines, a pyridinecarboxamide, a secondary carboxamide and an organochlorine compound. | |||
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