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| CAS: | 1801547-15-8 | Cat No: | JKN01127 | Purity: | 98% |
Note: All products of the company are for scientific research only, and do not provide products and services for any individual
Product Description
| CAS | 1801547-15-8 | Cat No | JKN01127 | |
| Name | PROTAC_ERRalpha | |||
| Synonyms | PROTAC_ERRalpha | |||
| Smiles | CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)(C)C)NC(=O)CCOCCN4C(=O)C(=CC5=CC(=C(C=C5)OC6=C(C=C(C=C6)C#N)C(F)(F)F)OC)SC4=O)O | |||
| Chemical Name | (2S,4R)-1-[(2S)-2-[3-[2-[5-[[4-[4-cyano-2-(trifluoromethyl)phenoxy]-3-methoxyphenyl]methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]ethoxy]propanoylamino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide | |||
| Formula | C46H47F3N6O9S2 | MWt | 949.0 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | PROTAC_ERRα is a VHL-based PROTAC targeting estrogen-related receptor alpha (ERRα) for degradation. ERRα plays central roles in the regulation of cellular energy homeostasis by controlling the transcription of genes involved in glucose and fatty acid metabolism and mitochondrial biogenesis. | |||
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