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| CAS: | 2417370-39-7 | Cat No: | JKN03125 | Purity: | 98% |
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Product Description
| CAS | 2417370-39-7 | Cat No | JKN03125 | |
| Name | PROTAC BRD4 degrader for PAC-1 | |||
| Synonyms | PROTAC BRD4 degrader for PAC-1 | |||
| Smiles | CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)(C)C)NC(=O)CCCCCCCCCCNC(=O)C4=CC5=C(C=C4CS(=O)(=O)C)C6=CN(C(=O)C7=C6C(=CN7)CN5C8=C(C=C(C=N8)F)F)C)OC(=O)OCC(C)(C)SS(=O)(=O)C | |||
| Chemical Name | [(3R,5S)-1-[(2S)-2-[11-[[8-(3,5-difluoropyridin-2-yl)-15-methyl-4-(methylsulfonylmethyl)-14-oxo-8,12,15-triazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaene-5-carbonyl]amino]undecanoylamino]-3,3-dimethylbutanoyl]-5-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]pyrrolidin-3-yl] (2-methyl-2-methylsulfonylsulfanylpropyl) carbonate | |||
| Formula | C62H77F2N9O12S4 | MWt | 1306.6 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | PROTAC BRD4 Degrader-24 (compound 5) is a PROTAC-linker conjugate for PAC, which contains the chimeric BET degrader GNE-987 and a disulfide-containing linker. | |||
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