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| CAS: | 1092364-38-9 | Cat No: | JKN03197 | Purity: | 98% |
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Product Description
| CAS | 1092364-38-9 | Cat No | JKN03197 | |
| Name | Poziotinib | |||
| Synonyms | Poziotinib | |||
| Smiles | COC1=C(C=C2C(=C1)N=CN=C2NC3=C(C(=C(C=C3)Cl)Cl)F)OC4CCN(CC4)C(=O)C=C | |||
| Chemical Name | 1-[4-[4-(3,4-dichloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]oxypiperidin-1-yl]prop-2-en-1-one | |||
| Formula | C23H21Cl2FN4O3 | MWt | 491.3 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Poziotinib is a member of the class of quinazolines that is quinazoline substituted by (3,4-dichloro-2-fluorophenyl)amino, [1-(prop-2-enoyl)piperidin-4-yl]oxy, and methoxy groups at positions 4, 6, and 7, respectively. It is a potent and irreversible tyrosine kinase inhibitor targeting EGFR and HER2 with exon 20 insertion mutations. It has a role as an antineoplastic agent, an apoptosis inducer and an epidermal growth factor receptor antagonist. It is a member of quinazolines, a N-acylpiperidine, an aromatic ether, a diether, a secondary amino compound, a dichlorobenzene, a member of monofluorobenzenes, a substituted aniline and a member of acrylamides. | |||
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