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CAS: | 116839-68-0 | Cat No: | JKN00319 | Purity: | 98% |
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Product Description
CAS | 116839-68-0 | Cat No | JKN00319 | |
Name | Posiphen | |||
Synonyms | (+)-O-(Phenylcarbamoyl)eseroline | |||
Smiles | O=C(NC1=CC=CC=C1)OC2=CC([C@]3(CCN([C@]34[H])C)C)=C(C=C2)N4C | |||
Chemical Name | (3aR,8aS)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl phenylcarbamate | |||
Formula | C20H23N3O2 | MWt | 337.423 | |
Purity | 98% | Storage | Store at 4--8℃ | |
Description | Posiphen, also known as R-phenserine or (-)-Phenserine, is a selective, non-competitive inhibitor of acetylcholinesterase (AChE). (-)-Phenserine produces rapid, potent, and long-lasting AChE inhibition, in vivo. (-)-Phenserine attenuates soman-induced neuropathology. Posiphen is seen to reduce glutamate-mediated neuronal loss in co-cultures of primary cortical cells and microglia. |
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