Pharmaceutical intermediates

Jingkangen Biomedical provides different types of Pharmaceutical intermediates ranging from milligrams to kilograms scale (1000kg) with high quality and competitive prices.

Posiphen

CAS: 116839-68-0 Cat No: JKN00319 Purity: 98%

Note: All products of the company are for scientific research only, and do not provide products and services for any individual

Product Description

CAS 116839-68-0 Cat No JKN00319
Name Posiphen
Synonyms (+)-O-(Phenylcarbamoyl)eseroline
Smiles O=C(NC1=CC=CC=C1)OC2=CC([C@]3(CCN([C@]34[H])C)C)=C(C=C2)N4C
Chemical Name (3aR,8aS)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl phenylcarbamate
Formula C20H23N3O2 MWt 337.423
Purity 98% Storage Store at 4--8℃
Description Posiphen, also known as R-phenserine or (-)-Phenserine, is a selective, non-competitive inhibitor of acetylcholinesterase (AChE). (-)-Phenserine produces rapid, potent, and long-lasting AChE inhibition, in vivo. (-)-Phenserine attenuates soman-induced neuropathology. Posiphen is seen to reduce glutamate-mediated neuronal loss in co-cultures of primary cortical cells and microglia.

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