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+86 137 2013 4139
| CAS: | 1303420-67-8 | Cat No: | JKN00091 | Purity: | 98% |
Note: All products of the company are for scientific research only, and do not provide products and services for any individual
Product Description
| CAS | 1303420-67-8 | Cat No | JKN00091 | |
| Name | PLX5622 | |||
| Synonyms | PLX5622 | |||
| Smiles | CC1=CN=C2C(C(CC3=C(F)N=C(NCC4=CC(F)=CN=C4OC)C=C3)=CN2)=C1 | |||
| Chemical Name | 6-fluoro-N-((5-fluoro-2-methoxypyridin-3-yl)methyl)-5-((5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)pyridin-2-amine | |||
| Formula | C21H19F2N5O | MWt | 395.410 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | PLX5622 is a highly selective brain penetrant and oral active CSF1R inhibitor. PLX5622 has been shown to eliminate microglia from the brain, which can be sustained in wild-type and the Alzheimer's disease model mice (3xTg-AD model). In the AD model PLX5622 prevents microglial association with amyloid β plaques and improves cognition. | |||
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