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| CAS: | 571190-30-2 | Cat No: | JKN03270 | Purity: | 98% |
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Product Description
| CAS | 571190-30-2 | Cat No | JKN03270 | |
| Name | Palbociclib | |||
| Synonyms | Palbociclib | |||
| Smiles | CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C | |||
| Chemical Name | 6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one | |||
| Formula | C24H29N7O2 | MWt | 447.5 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Palbociclib is a member of the class of pyridopyrimidines that is 2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-d]pyrimidin-7-one bearing additional methyl, acetyl and cyclopentyl substituents at positions 5, 6 and 8 respectively. It is used in combination with letrozole for the treatment of metastatic breast cancer. It has a role as an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor and an antineoplastic agent. It is a pyridopyrimidine, an aminopyridine, a secondary amino compound, a member of piperidines, an aromatic ketone, a member of cyclopentanes and a tertiary amino compound. | |||
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