Pharmaceutical intermediates

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NRX-252262

CAS: 2438637-61-5 Cat No: JKN03249 Purity: 98%

Note: All products of the company are for scientific research only, and do not provide products and services for any individual

Product Description

CAS 2438637-61-5 Cat No JKN03249
Name NRX-252262
Synonyms NRX-252262
Smiles COC1=C(C=C2CN(CC2=C1)C(=O)C3=C(C=C(NC3=O)C(F)(F)F)SC4=C(C=CC=C4Cl)Cl)OC
Chemical Name 4-(2,6-dichlorophenyl)sulfanyl-3-(5,6-dimethoxy-1,3-dihydroisoindole-2-carbonyl)-6-(trifluoromethyl)-1H-pyridin-2-one
Formula C23H17Cl2F3N2O4S MWt 545.4
Purity 98% Storage Store at 4--8℃
Description NRX-252262 is a potent enhancer of the interaction between β-Catenin and the homologous E3 ligase SCFβ-TrCP, which can promote the degradation of β-catenin with EC50 of 3.8 nM.

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