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| CAS: | 2641216-67-1 | Cat No: | JKN03248 | Purity: | 98% |
Note: All products of the company are for scientific research only, and do not provide products and services for any individual
MK-1084 Powder for KRAS G12C Research
JKN Biochem supplies MK-1084 powder, also known as Calderasib, for KRAS G12C signaling pathway research and oncology drug discovery programs. With 98% purity, defined chemical identity, documentation support, and custom synthesis capability, JKN Biochem helps research laboratories and pharmaceutical teams source MK-1084 efficiently from research-scale quantities to larger project-based requirements.
MK-1084 is a high-value KRAS G12C research compound, and buyers usually need more than a product listing. JKN Biochem supports compound sourcing, analytical documentation, custom synthesis, scale-up evaluation, and global shipment coordination for pharmaceutical and biochemical research customers.
Focused product portfolio: APIs, pharmaceutical intermediates, small-molecule inhibitors, electronic materials, organic synthesis building blocks, and drug impurity reference standards.
Flexible supply capability: research-scale, gram-scale, kilogram-scale, and project-based custom production support.
Technical manufacturing network: R&D center, pilot plant, production base, stable cooperative factories, and experienced international trade support.
Quality documentation support: COA, SDS, HPLC, NMR, MS, and other analytical documents can be discussed according to batch and order requirements.
Custom synthesis service: structure-based inquiry, CAS-based sourcing, fine chemical synthesis, route evaluation, and scale-up coordination.
The following information helps procurement, R&D, and analytical teams verify the product identity of MK-1084 powder before quotation, purchase, or documentation review.
| Chemical Name | 19-chloro-22-(2,5-dimethyl-4-prop-2-enoylpiperazin-1-yl)-13,16-difluoro-3-propan-2-yl-8,11-dioxa-1,4,23,26-tetrazapentacyclo[16.6.2.02,7.012,17.021,25]hexacosa-2(7),3,5,12,14,16,18,20,22,25-decaen-24-one |
| SMILES | CC1CN(C(CN1C(=O)C=C)C)C2=NC(=O)N3C4=C(C=CN=C4C(C)C)OCCOC5=C(C=CC(=C5C6=C(C=C2C3=N6)Cl)F)F |
| Research Category | KRAS signaling pathway; KRAS G12C inhibitor; oncology research compound |
| Appearance | Powder or solid; final appearance should be confirmed by batch COA. |
| Recommended Use | For scientific research and chemical synthesis use only. Not for human, diagnostic, therapeutic, food, or veterinary use. |
MK-1084 is a selective KRAS G12C inhibitor used in studies of mutant KRAS-driven signaling. KRAS G12C is a clinically important oncogenic mutation involved in abnormal downstream pathway activation, including RAF-MEK-ERK signaling, which is closely associated with tumor cell growth and survival.
As a KRAS G12C research signaling pathway compound, MK-1084 powder is relevant for oncology pathway research, covalent inhibitor evaluation, cancer cell signaling studies, combination strategy exploration, and medicinal chemistry programs focused on RAS pathway modulation.
KRAS G12C signaling pathway research
RAS-RAF-MAPK-ERK pathway studies
Oncology drug discovery and target validation
Small-molecule inhibitor screening
Medicinal chemistry and SAR comparison projects
Analytical method development and reference compound evaluation
Custom synthesis and scale-up feasibility studies
When selecting an MK-1084 powder supplier, quality traceability and documentation are key decision factors. JKN Biochem can provide or discuss batch-related documents according to project requirements, helping researchers confirm purity, identity, handling, and storage information before use.
Storage: Store MK-1084 powder at 4–8℃ unless the batch label or COA specifies otherwise.
Packaging: Milligram, gram, and larger custom package sizes can be discussed according to project needs.
Handling: Handle in a qualified laboratory environment using appropriate PPE and institutional safety procedures.
Stability: Keep containers tightly sealed and protect from unsuitable temperature, moisture, and contamination.
Documentation: Request COA, SDS, and analytical data before shipment when required by your internal QA process.
JKN Biochem supports both direct inquiry and custom synthesis evaluation for MK-1084 and related KRAS pathway compounds. Please provide quantity, purity, timeline, and documentation requirements for accurate quotation.
Research-scale MK-1084 powder inquiry
Bulk inquiry for larger project requirements
Custom synthesis and route evaluation
Purity optimization and analytical method discussion
Gram-to-kilogram supply coordination
International shipping and export documentation support
MK-1084 is a specialized research compound. A reliable supplier should provide more than a catalog name: buyers need chemical identity, purity confirmation, documentation, realistic lead time, secure packaging, and communication throughout the order process.
MK-1084, also known as Calderasib, is a selective KRAS G12C inhibitor used for scientific research in oncology signaling pathways and small-molecule inhibitor studies.
The CAS number of MK-1084 is 2641216-67-1.
JKN Biochem lists MK-1084 with 98% purity. Please confirm final batch purity, test method, and analytical data with the COA before use.
Yes. JKN Biochem can evaluate bulk inquiry and custom synthesis requirements based on requested quantity, purity, analytical documentation, and delivery timeline.
No. MK-1084 supplied by JKN Biochem is for scientific research and chemical synthesis use only. It is not intended for human, diagnostic, therapeutic, food, or veterinary use.
Looking for an MK-1084 powder supplier? Send your required quantity, purity expectation, documentation needs, destination country, and target delivery schedule. JKN Biochem will evaluate availability, custom synthesis feasibility, lead time, packaging, and quotation details for MK-1084 CAS 2641216-67-1.
Send Inquiry NowNote: All products are for scientific research only and are not provided to individuals for personal use.
Product Description
| CAS | 2641216-67-1 | Cat No | JKN03248 | |
| Name | MK-1084 | |||
| Synonyms | MK-1084 | |||
| Smiles | CC1CN(C(CN1C(=O)C=C)C)C2=NC(=O)N3C4=C(C=CN=C4C(C)C)OCCOC5=C(C=CC(=C5C6=C(C=C2C3=N6)Cl)F)F | |||
| Chemical Name | 19-chloro-22-(2,5-dimethyl-4-prop-2-enoylpiperazin-1-yl)-13,16-difluoro-3-propan-2-yl-8,11-dioxa-1,4,23,26-tetrazapentacyclo[16.6.2.02,7.012,17.021,25]hexacosa-2(7),3,5,12,14,16,18,20,22,25-decaen-24-one | |||
| Formula | C32H31ClF2N6O4 | MWt | 637.1 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | MK-1084 is a selective KRAS G12C inhibitor currently in Phase I clinical trials | |||
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