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| CAS: | 228559-41-9 | Cat No: | JKN00361 | Purity: | 98% |
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Product Description
| CAS | 228559-41-9 | Cat No | JKN00361 | |
| Name | Ki8751 | |||
| Synonyms | Ki8751 | |||
| Smiles | COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC(=C(C=C3)NC(=O)NC4=C(C=C(C=C4)F)F)F | |||
| Chemical Name | 1-(2,4-difluorophenyl)-3-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-fluorophenyl]urea | |||
| Formula | C24H18F3N3O4 | MWt | 469.4 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Ki8751 is a potent, selective inhibitor of VEGFR-2 tyrosine kinase (IC50 = 0.9 nM). Displays some inhibitory activity towards c-Kit, PDGFR α and FGFR-2 (IC50 values range from 40 to 170 nM). | |||
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