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Home - Products-JKN Signaling Pathways- JBJ-04-125-02 R-isomer

JBJ-04-125-02 R-isomer

CAS:

2060610-53-7

Cat No:

JKN03495

Purity:

98%

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Product Description

CAS	2060610-53-7	Cat No	JKN03495
Name	JBJ-04-125-02 R-isomer
Synonyms	JBJ-04-125-02
Smiles	C1CN(CCN1)C2=CC=C(C=C2)C3=CC4=C(CN(C4=O)[C@H](C5=C(C=CC(=C5)F)O)C(=O)NC6=NC=CS6)C=C3
Chemical Name	(2R)-2-(5-fluoro-2-hydroxyphenyl)-2-[3-oxo-5-(4-piperazin-1-ylphenyl)-1H-isoindol-2-yl]-N-(1,3-thiazol-2-yl)acetamide
Formula	C29H26FN5O3S	MWt	543.6
Purity	98%	Storage	Store at 4--8℃
Description	JBJ-04-125-02 R-isomer, the R-enantiomer ofJBJ-04-125-02, is a novel, highly potent, mutant-specific, allosteric and orally bioavailable EGFR inhibitor with an IC50 of 0.26 nM for EGFRL858R/T790M.

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