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| CAS: | 142880-36-2 | Cat No: | JKN00231 | Purity: | 98% |
Note: All products of the company are for scientific research only, and do not provide products and services for any individual
Product Description
| CAS | 142880-36-2 | Cat No | JKN00231 | |
| Name | Ilomastat | |||
| Synonyms | GM6001 | |||
| Smiles | O=C(NC)[C@@H](NC([C@@H](CC(NO)=O)CC(C)C)=O)CC1=CNC2=CC=CC=C21 | |||
| Chemical Name | (R)-N1-((S)-3-(1H-indol-3-yl)-1-(methylamino)-1-oxopropan-2-yl)-N4-hydroxy-2-isobutylsuccinamide | |||
| Formula | C20H28N4O4 | MWt | 388.461 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Ilomastat, also known as GM6001 and galardin, is a broad-spectrum matrix metalloproteinase inhibitor with potential anticancer activity. GM6001 is a member of the hydroxamic acid class of reversible metallopeptidase inhibitors. The anionic state of the hydroxamic acid group forms a bidentate complex with the active site zinc. Examples of enzymes that ilomastat inhibit include thermolysin, peptide deformylase, and anthrax lethal factor endopeptidase (LF) produced by the bacterium Bacillus anthracis. | |||
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