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| CAS: | 808118-40-3 | Cat No: | JKN03620 | Purity: | 98% |
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Product Description
| CAS | 808118-40-3 | Cat No | JKN03620 | |
| Name | FG-4592 | |||
| Synonyms | Roxadustat | |||
| Smiles | CC1=C2C=C(C=CC2=C(C(=N1)C(=O)NCC(=O)O)O)OC3=CC=CC=C3 | |||
| Chemical Name | 2-[(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)amino]acetic acid | |||
| Formula | C19H16N2O5 | MWt | 352.3 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Roxadustat is an N-acylglycine resulting from the formal condensation of the amino group of glycine with the carboxy group of 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylic acid. It is an inhibitor of hypoxia inducible factor prolyl hydroxylase (HIF-PH). It has a role as an EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor and an EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor. It is a member of isoquinolines, an aromatic ether and a N-acylglycine. | |||
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