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| CAS: | 574013-66-4 | Cat No: | JKN00192 | Purity: | 98% |
Note: All products of the company are for scientific research only, and do not provide products and services for any individual
Product Description
| CAS | 574013-66-4 | Cat No | JKN00192 | |
| Name | Fexaramine | |||
| Synonyms | fexaramine | |||
| Smiles | O=C(OC)/C=C/C1=CC=CC(N(C(C2CCCCC2)=O)CC3=CC=C(C4=CC=C(N(C)C)C=C4)C=C3)=C1 | |||
| Chemical Name | methyl (E)-3-(3-(N-((4'-(dimethylamino)-[1,1'-biphenyl]-4-yl)methyl)cyclohexanecarboxamido)phenyl)acrylate | |||
| Formula | C32H36N2O3 | MWt | 498.65 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Fexaramine is an agonist of the farnesoid X receptor (FXR), which is a bile acid-activated nuclear receptor that controls bile-acid synthesis, conjugation and transport, as well as lipid metabolism through actions in the liver and intestine. Fexaramine has 100-fold greater affinity for FXR than natural compounds and described the genomic targets and binding site on FXR. When administered orally to mice, fexaramine produced selective actions through FXR receptors in the intestines. | |||
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