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| CAS: | 169869-90-3 | Cat No: | JKN03444 | Purity: | 98% |
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Product Description
| CAS | 169869-90-3 | Cat No | JKN03444 | |
| Name | exatecan mesylate anhydrous | |||
| Synonyms | Exatecan mesylate | |||
| Smiles | CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C5[C@H](CCC6=C5C(=CC(=C6C)F)N=C4C3=C2)N)O.CS(=O)(=O)O | |||
| Chemical Name | (10S,23S)-23-amino-10-ethyl-18-fluoro-10-hydroxy-19-methyl-8-oxa-4,15-diazahexacyclo[14.7.1.02,14.04,13.06,11.020,24]tetracosa-1,6(11),12,14,16,18,20(24)-heptaene-5,9-dione;methanesulfonic acid | |||
| Formula | C25H26FN3O7S | MWt | 531.6 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Exatecan Mesylate Anhydrous is the anhydrous, mesylate salt form of exatecan, a semisynthetic, water-soluble derivative of camptothecin, with antineoplastic activity. Upon administration, exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting re-ligation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. | |||
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