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CAS: | 356057-34-6 | Cat No: | JKN00629 | Purity: | 98% |
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Product Description
CAS | 356057-34-6 | Cat No | JKN00629 | |
Name | Darapladib | |||
Synonyms | Darapladib | |||
Smiles | CCN(CC)CCN(CC1=CC=C(C=C1)C2=CC=C(C=C2)C(F)(F)F)C(=O)CN3C4=C(CCC4)C(=O)N=C3SCC5=CC=C(C=C5)F | |||
Chemical Name | N-[2-(diethylamino)ethyl]-2-[2-[(4-fluorophenyl)methylsulfanyl]-4-oxo-6,7-dihydro-5H-cyclopenta[d]pyrimidin-1-yl]-N-[[4-[4-(trifluoromethyl)phenyl]phenyl]methyl]acetamide | |||
Formula | C36H38F4N4O2S | MWt | 666.8 | |
Purity | 98% | Storage | Store at 4--8℃ | |
Description | Darapladib is a substituted pyrimidone with inhibitory activity towards lipoprotein-associated phospholipase-A2 (Lp-PLA2), an important regulator of lipid metabolism and inflammation that circulates with lipoprotein particles and is carried into the arterial wall with low-density lipoprotein particles during the progression of atherosclerosis. |
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