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| CAS: | 960539-70-2 | Cat No: | JKN00275 | Purity: | 98% |
Note: All products of the company are for scientific research only, and do not provide products and services for any individual
Product Description
| CAS | 960539-70-2 | Cat No | JKN00275 | |
| Name | Daprodustat | |||
| Synonyms | GSK-1278863 | |||
| Smiles | O=C(O)CNC(C(C(N1C2CCCCC2)=O)C(N(C3CCCCC3)C1=O)=O)=O | |||
| Chemical Name | (1,3-dicyclohexyl-2,4,6-trioxohexahydropyrimidine-5-carbonyl)glycine | |||
| Formula | C19H27N3O6 | MWt | 393.440 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Daprodustat, also known as GSK1278863, is a novel HIF-prolyl hydroxylase inhibitor. Hypoxia inducible factor (HIF) stabilization by HIF-prolyl hydroxylase (PHD) inhibitors may improve ischemic conditions such as peripheral artery disease (PAD). Short-term treatment with a novel HIF-prolyl hydroxylase inhibitor (GSK1278863) failed to improve measures of performance in subjects with claudication-limited peripheral artery disease. | |||
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