Pharmaceutical intermediates

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Dabigatran Etexilate Mesylate

CAS: 872728-81-9 Cat No: JKN00618 Purity: 98%

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Product Description

CAS 872728-81-9 Cat No JKN00618
Name Dabigatran Etexilate Mesylate
Synonyms Dabigatran etexilate mesylate
Smiles CCCCCCOC(=O)NC(=N)C1=CC=C(C=C1)NCC2=NC3=C(N2C)C=CC(=C3)C(=O)N(CCC(=O)OCC)C4=CC=CC=N4.CS(=O)(=O)O
Chemical Name ethyl 3-[[2-[[4-(N-hexoxycarbonylcarbamimidoyl)anilino]methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoate;methanesulfonic acid
Formula C35H45N7O8S MWt 723.8
Purity 98% Storage Store at 4--8℃
Description Dabigatran Etexilate Mesylate is an orally available mesylate salt form of the etexilate prodrug of dabigatran, a benzimidazole and direct thrombin inhibitor with anticoagulant activity. Upon administration, dabigatran etexilate is hydrolyzed by esterases and is converted into dabigatran. Dabigatran reversibly binds to and inhibits the activity of thrombin, a serine protease that converts fibrinogen into fibrin. This disrupts the coagulation cascade and inhibits the formation of blood clots.

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